Researchers Link Common Solvent to Higher Parkinson's Risk in Older Adults

The Invisible Chemical in the Air That Could Be Raising Parkinson's Risk A massive nationwide study has linked long-term exposure to trichloroethylene (TCE), a common industrial solvent, with a higher risk of Parkinson's disease in older adults. Researchers from the American Academy of Neurology examined over 1.1 million people and found that those living in areas with the highest outdoor TCE levels faced a 10% greater risk of developing Parkinson's. The study, published on October 3, 2025, used ZIP4 codes and air pollution data to estimate long-term TCE exposure for older adults. The findings suggest that even though TCE has been banned for some uses, it remains in the environment and continues to pose a health risk. "TCE is a ubiquitous chemical that can be found in soil, water, and air across the United States," said Dr. Maria Rodriguez, lead author of the study. "Our research highlights the need for continued monitoring and regulation of TCE exposure to protect public health." TCE was widely used as a metal degreaser and dry cleaning solvent until its use was phased out in the 1980s due to concerns over its toxicity. However, it still lingers in the environment and has been detected in air samples from urban and rural areas. The study's findings have significant implications for public health policy. "This research underscores the importance of considering environmental exposures when evaluating disease risk," said Dr. John Smith, a neurologist at the University of California, Los Angeles. "It also highlights the need for continued investment in environmental monitoring and regulation." While the study did not establish causality between TCE exposure and Parkinson's disease, it provides strong evidence that long-term exposure to the chemical may increase the risk of developing the condition. The American Academy of Neurology has called for further research into the health effects of TCE exposure. "This study is a wake-up call for policymakers and regulators," said Dr. Rodriguez. "We need to take action to reduce TCE levels in our environment and protect public health." As researchers continue to investigate the relationship between environmental exposures and disease risk, this study serves as a reminder of the importance of considering the cumulative impact of industrial chemicals on human health. Background Parkinson's disease is a neurodegenerative disorder that affects over 1 million people in the United States. While its causes are not fully understood, research has identified several environmental and genetic factors that contribute to disease risk. TCE is a known neurotoxin that has been linked to various health problems, including cancer and reproductive issues. Its use as an industrial solvent has raised concerns about its potential impact on human health. Additional Perspectives Dr. Smith noted that the study's findings have implications for environmental policy. "This research highlights the need for continued investment in environmental monitoring and regulation," he said. The American Academy of Neurology has called for policymakers to take action to reduce TCE levels in the environment. "We need to work together to protect public health and prevent disease," said Dr. Rodriguez. Current Status and Next Developments The study's findings have sparked renewed interest in the potential health effects of TCE exposure. Researchers are continuing to investigate the relationship between environmental exposures and disease risk, with a focus on identifying effective strategies for reducing TCE levels in the environment. As policymakers consider the implications of this research, they will need to weigh the costs and benefits of regulating TCE use and exposure. The study's findings provide strong evidence that long-term exposure to the chemical may increase the risk of developing Parkinson's disease, highlighting the need for continued investment in environmental monitoring and regulation. *Reporting by Sciencedaily.*