Chiefs Fall to Bills for Fifth Straight Regular-Season Loss as Defense Crumbles

The Kansas City Chiefs suffered their fifth consecutive regular-season loss to the Buffalo Bills on November 2, 2025, as their defense faltered in a 28-21 defeat. The loss marks the latest chapter in a long-standing rivalry between the two teams, with quarterback Josh Allen leading the Bills to victory once again. Patrick Mahomes, the Chiefs' star quarterback, acknowledged the significance of the loss, stating, "It always comes down to these certain plays." He was referring to the final seconds of the game, when Mahomes attempted a Hail Mary pass from 40 yards away, but it fell short of the end zone. The play was a microcosm of the game, which was marked by a series of crucial mistakes by the Chiefs' defense. The Bills' victory was their fifth consecutive regular-season win over the Chiefs, dating back to 2020. However, the Chiefs have enjoyed more success against the Bills in the postseason, with a 4-0 record in their playoff matchups. The latest regular-season installment was a closely contested game, with the Bills' Josh Allen outdueling Mahomes in a battle of two of the NFL's top quarterbacks. The rivalry between the Chiefs and Bills has been fueled by the intense competition between Allen and Mahomes, who have faced off 10 times since 2020. Allen has had the upper hand in the regular season, but Mahomes has consistently performed well against the Bills in the playoffs. The two quarterbacks have developed a deep respect for each other, with Mahomes praising Allen's skills after the game. The loss marks a setback for the Chiefs, who had been riding a high after a strong start to the season. The team's defense, which had been a strength earlier in the year, struggled to contain the Bills' high-powered offense. The loss also raises questions about the Chiefs' ability to contend for a championship in the highly competitive AFC. The Bills, on the other hand, have solidified their position as one of the top teams in the AFC. Their victory over the Chiefs was a statement win, demonstrating their ability to compete with the best teams in the league. The team's success has been fueled by the strong play of Allen, who has developed into one of the top quarterbacks in the NFL. The rivalry between the Chiefs and Bills is expected to continue, with the two teams set to face off again in the regular season. The game will be closely watched, as it will provide further insight into the teams' strengths and weaknesses. The outcome of the game will also have significant implications for the AFC playoff picture, with both teams vying for a spot in the postseason.