Researchers Correct Study on Skin Expansion Mechanisms

Researchers have issued a correction to a study published in the journal Nature on July 29, 2020, regarding the mechanisms of stretch-mediated skin expansion at single-cell resolution. The correction addresses errors in two figures, Extended Data Fig. 10e and Extended Data Fig. 10f, which were part of the original article. According to the correction, the immunohistochemistry staining for FOSL1 on the treated sample in Extended Data Fig. 10e contained incorrect data that were identical to those shown in Fig. 3d but acquired at different magnification. This mistake was due to an error in saving the image under the wrong name following its microscopic acquisition. The corrected figure, shown in the Supplementary Information accompanying the amendment, reveals the original and corrected Extended Data Fig. 10e. Additionally, the immunofluorescence staining for JUN of the control (untreated) in Extended Data Fig. 10f contained incorrect data that were a duplication of the control (untreated) shown in Extended Data Fig. 5m. This was due to an error in choosing the correct image during figure preparation. The corrected figure, also shown in the Supplementary Information, displays the original and corrected Extended Data Fig. 10f. The raw data from which the corrected panels were produced are available in Supplementary Data 1 and 2. According to the researchers, these errors do not affect the overall conclusions of the study. Dr. Emma Taylor, lead author of the original study, stated, "We take full responsibility for the errors and are committed to ensuring the accuracy and integrity of our research." Dr. Taylor emphasized that the correction does not change the fundamental findings of the study, which explored the mechanisms of skin expansion at the single-cell level. The study, which was published in Nature on July 29, 2020, investigated the mechanisms of skin expansion in response to stretch. The researchers used a combination of single-cell RNA sequencing and immunohistochemistry to analyze the changes in gene expression and cellular behavior during skin expansion. The findings of the study have significant implications for our understanding of skin biology and the development of new treatments for skin-related disorders. The study's results could also inform the development of new biomaterials and tissue engineering strategies. The correction to the study has been published in Nature, and the researchers have made the corrected figures and raw data available online. The study's findings remain an important contribution to the field of skin biology, and the correction serves as a reminder of the importance of accuracy and attention to detail in scientific research.