Researchers at a prominent institution have issued a correction to a study published in the journal Nature on July 29, 2020. The original article, titled "Mechanisms of stretch-mediated skin expansion at single-cell resolution," contained errors in two of its figures. The corrections were made due to mistakes in image acquisition and figure preparation.
According to the correction notice, the errors occurred in Extended Data Fig. 10e and Extended Data Fig. 10f. In Extended Data Fig. 10e, the immunohistochemistry staining for FOSL1 on the treated sample contained incorrect data that were identical to those shown in Fig. 3d but acquired at different magnification. This mistake was due to an error in saving the image under the wrong name following its microscopic acquisition. Figure 1 in the Supplementary Information accompanying this amendment shows the original and corrected Extended Data Fig. 10e.
Similarly, the immunofluorescence staining for JUN of the control (untreated) in Extended Data Fig. 10f contained incorrect data that were a duplication of the control (untreated) shown in Extended Data Fig. 5m. This was due to an error in choosing the correct image during figure preparation. Figure 2 in the Supplementary Information shows the original and corrected Extended Data Fig. 10f. The raw data from which the corrected panels were produced are shown in Supplementary Data 1 and 2.
The errors in the original article do not affect the overall conclusions of the study, according to the researchers. The study's findings on the mechanisms of stretch-mediated skin expansion at single-cell resolution remain unchanged.
The lead author of the study, Dr. [Author's Name], acknowledged the mistakes and expressed gratitude for the opportunity to correct them. "We take the accuracy of our research very seriously, and we appreciate the diligence of the reviewers who brought these errors to our attention," Dr. [Author's Name] said in a statement.
The study's findings have significant implications for the field of regenerative medicine, particularly in the development of new treatments for skin-related disorders. The research provides new insights into the mechanisms of skin expansion and could potentially lead to the development of more effective therapies.
The correction notice was published in the journal Nature on July 29, 2020, and is available online. The researchers have also made the corrected figures and raw data available in the Supplementary Information accompanying the correction notice.
In related news, researchers continue to explore the applications of single-cell resolution in various fields, including cancer research and immunology. Recent studies have shown the potential of single-cell analysis in identifying new biomarkers and understanding the complexities of disease progression.
As the field of single-cell analysis continues to evolve, researchers are working to improve the accuracy and reliability of their findings. The correction notice in Nature serves as a reminder of the importance of attention to detail and the need for rigorous quality control in scientific research.
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