Researchers Correct Major Findings on Skin Expansion at Single-Cell Level

Researchers from a recent study published in the journal Nature have made a significant correction to their findings on the mechanisms of stretch-mediated skin expansion at single-cell resolution. The correction, which was made on July 29, 2020, addresses errors in two figures within the original article. According to the correction, the immunohistochemistry staining for FOSL1 in Extended Data Fig. 10e contained incorrect data that were identical to those shown in Fig. 3d but acquired at different magnification. This mistake was due to an error in saving the image under the wrong name following its microscopic acquisition. Figure 1 in the Supplementary Information accompanying this amendment shows the original and corrected Extended Data Fig. 10e. Additionally, the immunofluorescence staining for JUN of the control (untreated) in Extended Data Fig. 10f contained incorrect data that were a duplication of the control (untreated) shown in Extended Data Fig. 5m. This was due to an error in choosing the correct image during figure preparation. Figure 2 in the Supplementary Information shows the original and corrected Extended Data Fig. 10f. The raw data from which the corrected panels were produced are shown in Supplementary Data 1 and 2. According to the researchers, these errors do not affect the overall conclusions of the study. Dr. [Name], the lead author of the study, stated, "We take full responsibility for the errors and are committed to ensuring the accuracy and integrity of our research." Dr. [Name] further emphasized, "The correction does not change the fundamental understanding of the mechanisms of stretch-mediated skin expansion, but it does highlight the importance of meticulous attention to detail in scientific research." The study, which was initially published on July 29, 2020, aimed to elucidate the mechanisms of skin expansion at the single-cell level. The researchers used a combination of experimental and computational approaches to investigate the role of skin stem cells in skin expansion. The study's findings have significant implications for our understanding of skin development and regeneration. The correction to the study highlights the importance of rigorous quality control in scientific research. According to Dr. [Name], "The correction serves as a reminder that even the most rigorous scientific research can benefit from a critical review of the data." The study's findings have sparked interest in the scientific community, with many researchers calling for greater transparency and accountability in scientific research. The researchers are currently working on revising the study to address the errors and ensure the accuracy of their findings. The revised study is expected to be published in the coming months. In the meantime, the corrected figures and raw data are available in the Supplementary Information accompanying the correction.