Researchers Correct Mistake in Groundbreaking Weight Loss Study

Researchers at the NYU Grossman School of Medicine have corrected a mistake in a recent study published in the journal Nature. The correction was made to Extended Data Fig. 2f,g, which contained a copy-paste error involving the incorrect panels for Day 3 Het No Cys and Day 3 KO Ctrl. The error was identified as a result of a copy-paste mistake, and the figure has now been updated with the correct panels in both the HTML and PDF versions of the article. According to the correction notice, the mistake did not affect the conclusions of the figure or the overall paper. The study, which was published on May 21, 2025, investigated the effects of cysteine deficiency on fat metabolism and weight loss. The researchers found that cysteine deficiency led to rapid weight loss in mice, and the study aimed to unravel the underlying mechanisms of this phenomenon. Alan Varghese, one of the authors of the study, acknowledged the mistake and stated that the correction was made to ensure the accuracy of the research. "We take all errors seriously and are committed to maintaining the highest standards of research integrity," Varghese said. "The correction was made promptly, and we are confident that it does not affect the overall conclusions of the study." The study, which was a collaborative effort between researchers from the Department of Cell Biology and the Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine, aimed to shed light on the role of cysteine in fat metabolism. Cysteine is an amino acid that plays a crucial role in various cellular processes, including the synthesis of proteins and the regulation of energy metabolism. The researchers used a mouse model to study the effects of cysteine deficiency on fat metabolism and weight loss. They found that cysteine deficiency led to rapid weight loss in mice, and the study aimed to unravel the underlying mechanisms of this phenomenon. The study's findings have important implications for our understanding of the role of cysteine in human health and disease. The correction notice was published on May 21, 2025, and the updated figure is now available in both the HTML and PDF versions of the article. The study's authors are committed to maintaining the highest standards of research integrity and are confident that the correction does not affect the overall conclusions of the study. As of now, the study's findings remain unchanged, and the researchers continue to investigate the role of cysteine in fat metabolism and weight loss. Further research is needed to fully understand the implications of the study's findings and to explore potential therapeutic applications.