Researchers Correct Cancer Study, Uncover Hidden Immune System Link

Researchers have made a crucial correction to a study published in the journal Nature, shedding new light on the relationship between cancer and the immune system. The correction, made on September 3, 2020, involves a figure in the study that was mistakenly duplicated, leading to an inaccurate representation of the data. According to the correction, the mistake occurred in Extended Data Fig. 1j, which was meant to show the results of a flow cytometry experiment. However, the figure was inadvertently duplicated from a different condition, A375 sup, instead of the intended condition, SupSer. The corrected figure has been updated in both the HTML and PDF versions of the article. The original study, published on September 2, 2020, explored the role of the SLC43A2 gene in cancer metabolism and its impact on the immune system. The researchers, led by Yingjie Bian and Wei Li from the University of Michigan School of Medicine, discovered that the SLC43A2 gene alters the metabolism of methionine in T cells, which are a type of immune cell. This alteration affects the methylation of histones, which are proteins that play a crucial role in gene expression. The correction does not change the overall findings of the study, but it does provide a more accurate representation of the data. The researchers have acknowledged the mistake and expressed gratitude for the opportunity to correct it. "We appreciate the diligence of the reviewers and the editors in bringing this to our attention," said Wei Li, one of the lead authors of the study. "The correction ensures that our findings are presented accurately and with the highest level of integrity." The study has significant implications for our understanding of cancer metabolism and its relationship to the immune system. Cancer cells often develop ways to evade the immune system, and this study provides new insights into how they do so. The researchers hope that their findings will contribute to the development of new cancer therapies that target the metabolic pathways involved in cancer progression. The correction has been made available online, and the study remains a valuable contribution to the field of cancer research. As research continues to advance, scientists will continue to refine their understanding of the complex relationships between cancer cells and the immune system. The University of Michigan School of Medicine has confirmed that the correction has been made and that the study remains a significant contribution to the field of cancer research. The researchers involved in the study are continuing their work, exploring new avenues of research that may lead to breakthroughs in cancer treatment.