Researchers Correct Cancer Study Mistake, Reveal New Insights into T Cell Metabolism

Researchers at the University of Michigan School of Medicine have corrected an error in a previous study published in the journal Nature. The correction, made on September 3, 2020, involved a mistake in Extended Data Fig. 1j, where a representative flow cytometry dot plot for a specific condition was mistakenly duplicated from another condition. The corrected figure has been updated in both the HTML and PDF versions of the article. According to the correction, the error occurred due to a figure preparation mistake. The researchers, led by Yingjie Bian and Wei Li, who contributed equally to the study, acknowledged the mistake and took steps to rectify it. "We strive for accuracy in our research and appreciate the opportunity to correct this error," said Bian and Li in a statement. The original study, published on September 2, 2020, explored the relationship between cancer metabolism and tumour immunology. The researchers found that the SLC43A2 gene, which is often altered in cancer cells, affects T cell methionine metabolism and histone methylation. This discovery has significant implications for understanding cancer biology and developing new treatments. The study was conducted at the Department of Surgery and the Center of Excellence for Cancer Immunology and Immunotherapy at the University of Michigan School of Medicine. The researchers used a variety of techniques, including flow cytometry and mass spectrometry, to analyze the effects of SLC43A2 on T cell metabolism and histone methylation. The correction of the error in the study is a testament to the researchers' commitment to accuracy and transparency. "We are committed to ensuring the integrity of our research and appreciate the opportunity to correct this error," said Weiping Zou, a co-author of the study and director of the Center of Excellence for Cancer Immunology and Immunotherapy. The corrected study is now available online and in print. The researchers plan to continue their investigation into the relationship between cancer metabolism and tumour immunology, with the goal of developing new treatments for cancer patients. In related news, the University of Michigan School of Medicine has announced plans to continue its research into cancer biology and immunotherapy. The school's Rogel Cancer Center is a leading center for cancer research and treatment, and the university is committed to advancing our understanding of cancer and developing new treatments. The corrected study is a significant contribution to the field of cancer research and highlights the importance of accuracy and transparency in scientific research.