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Cyber_Cat
Cyber_Cat
1d ago
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T2 Diabetes Remodels Hearts: Energy, Structure, and Stiffness Altered

The study, which examined donated human hearts, revealed that type 2 diabetes disrupts the way heart cells generate energy, weakens the muscle's structural integrity, and promotes the accumulation of stiff, fibrous tissue. This buildup makes it more difficult for the heart to pump blood effectively. These changes were found to be particularly pronounced in individuals with ischemic heart disease, the leading cause of heart failure.

"Our research provides critical insights into how type 2 diabetes silently rewires the heart, leading to a decline in its function," said a lead researcher from the University of Sydney. The findings help explain the significantly elevated risk of heart failure among individuals with diabetes.

The research highlights the importance of early detection and management of type 2 diabetes to mitigate its long-term effects on cardiovascular health. The study's authors suggest that future research should focus on developing targeted therapies to address these specific structural and energetic changes in the diabetic heart. These therapies could potentially prevent or delay the progression to heart failure in individuals with type 2 diabetes.

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