In a correction issued today, Nature addressed an error in the original publication of the article "Rewiring an olfactory circuit by altering cell-surface combinatorial code," which appeared online on November 19, 2025. The correction involves Figure 1h, where the bottom three panels in the klg RNAi column were found to be duplicates of images from Figure 1c.
The journal has updated both the HTML and PDF versions of the article with the correct figures. The research, focusing on axon and dendritic guidance within neural circuits, was conducted by Cheng Lyu, Zhuoran Li, Chuanyun Xu, Jordan Kalai, and Liqun Luo from Stanford University's Department of Biology and Howard Hughes Medical Institute. Li, Xu, and Kalai are also affiliated with the Biology Graduate Program at Stanford. Liqun Luo is the corresponding author.
According to Nature, the error was identified post-publication and promptly addressed to maintain the integrity of the scientific record. While the correction is relatively minor, the incident highlights the rigorous standards of peer-reviewed scientific publications and the commitment to accuracy. The original article explores how manipulating cell-surface proteins can redirect neural connections in the olfactory system, offering potential insights into brain development and neurological disorders.
Industry insiders suggest that such corrections, while not uncommon, underscore the importance of careful image handling and data verification in scientific research. The field of neural circuit research is rapidly advancing, with significant implications for understanding and treating conditions like autism and Alzheimer's disease. The corrected article is available on Nature's website, ensuring that researchers and the public have access to accurate information.
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