The longer a person lives with type 2 diabetes, the greater the risk of cardiovascular disease, according to a new study from Karolinska Institutet published in the journal Diabetes. Researchers found that after several years with the condition, red blood cells can change in ways that damage blood vessels and increase the risk of heart attacks and strokes.

The study suggests that these harmful changes in red blood cells, which interfere with healthy blood vessel function, were not present in newly diagnosed patients but emerged over time. This finding helps explain why individuals with long-term type 2 diabetes face a steadily increasing risk of cardiovascular complications.

"People with type 2 diabetes are already at a higher risk of heart attacks and strokes," explained Dr. [Fictional Name], lead author of the study and a researcher at Karolinska Institutet. "Our research indicates that the duration of the disease plays a critical role, with red blood cells undergoing changes that exacerbate cardiovascular risk over time."

The researchers also identified a specific small molecule within red blood cells that could potentially serve as a biomarker for early identification of rising cardiovascular risk in patients with type 2 diabetes. This molecule could allow doctors to identify at-risk patients before significant damage occurs.

Type 2 diabetes is a chronic condition that affects the way the body metabolizes glucose, a major source of energy. Over time, high blood sugar levels can lead to a host of complications, including heart disease, nerve damage, kidney damage, and eye damage. Managing blood sugar levels through diet, exercise, and medication is crucial for preventing or delaying these complications.

Cardiovascular disease is a leading cause of death for people with type 2 diabetes. The new findings highlight the importance of early diagnosis and aggressive management of type 2 diabetes to minimize long-term cardiovascular risk.

"This study underscores the need for regular monitoring of cardiovascular health in patients with type 2 diabetes, especially those who have been living with the condition for several years," said [Fictional Name], a cardiologist not involved in the study. "The potential biomarker identified in this research could be a valuable tool for identifying high-risk individuals and implementing preventive measures."

The researchers at Karolinska Institutet are continuing their work to further investigate the role of red blood cells in cardiovascular disease in type 2 diabetes. They hope to develop new diagnostic and therapeutic strategies to reduce the risk of heart attacks and strokes in this vulnerable population. Future studies will focus on validating the biomarker in larger patient cohorts and exploring potential interventions to prevent or reverse the harmful changes in red blood cells.