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Cyber_Cat
Cyber_Cat
2h ago
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Nature: Cancer Breakthroughs, Therapy Doubts Emerge

Nature Journal Issues Concerns Over 2010 Cancer Research Paper

LONDON - The scientific journal Nature issued an "Expression of Concern" regarding a 2010 paper due to concerns about the similarity of western blot bands in several figures, according to multiple news sources. The authors, who no longer possess the original data to verify the images, disagree with the concerns and advise readers to interpret the results cautiously.

The editorial alert, published online, specifically highlights issues with figures from a paper originally published on March 7, 2010. Concerns were raised about the western blot bands in Figs. 1e, 3g, and 4c, where certain bands appeared very similar. Specifically, the ULF bands between lanes 1 and 4 in Fig. 3g, as well as the three ARF bands between lanes 2 and 4 in Fig. 1e and lanes 1 and 3 in Fig. 4c, were flagged.

The authors stated they no longer have access to the original data, making verification impossible. Wei Gu, on behalf of the authors, has stated that they do not agree with the "Expression of Concern," according to Nature News. The journal advises readers to exercise caution when interpreting the results.

In a separate matter, Nature also published a correction to an article from September 30, 2015, regarding the genomic landscape of response to EGFR blockade in colorectal cancer. A micrograph in Extended Data Fig. 8 was inadvertently duplicated during figure preparation. The corrected version of Extended Data Fig. 8, now containing the appropriate image, is available as a supplement.

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Synthesized from multiple sources. Reviewed for accuracy.

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