People living with type 2 diabetes face an increased risk of cardiovascular disease, and a new study published in the journal Diabetes suggests changes in red blood cells may contribute to this heightened danger. Researchers at Karolinska Institutet found that after several years with the condition, red blood cells can begin to interfere with healthy blood vessel function.
The study indicated this harmful shift in red blood cell behavior was not present in newly diagnosed patients but emerged over time. This suggests the duration of type 2 diabetes plays a significant role in the development of cardiovascular complications.
According to the research team, a specific small molecule inside blood cells may serve as a future biomarker for identifying cardiovascular risk early on. This could potentially allow for earlier interventions and more personalized treatment strategies for patients with type 2 diabetes.
Type 2 diabetes is a chronic condition that affects the way the body metabolizes sugar (glucose), and over time, high blood sugar levels can lead to disorders of the circulatory, nervous, and immune systems. People with type 2 diabetes are at a higher risk of heart attacks and strokes, making the identification of factors contributing to this risk crucial.
The Karolinska Institutet researchers believe their findings offer a potential explanation for the increased cardiovascular risk associated with long-term type 2 diabetes. While the exact mechanisms by which these red blood cell changes damage blood vessels are still being investigated, the study provides a valuable starting point for future research.
The identification of a potential biomarker could have significant practical implications for managing patients with type 2 diabetes. Early detection of cardiovascular risk would allow healthcare professionals to implement preventative measures, such as lifestyle modifications or medication, to reduce the likelihood of heart attacks and strokes.
Further research is needed to validate these findings and to fully understand the role of red blood cell changes in the development of cardiovascular disease in people with type 2 diabetes. However, this study represents a significant step forward in understanding the complex relationship between diabetes and heart health.
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