People living with type 2 diabetes face an increased risk of cardiovascular disease, and a new study published in the journal Diabetes suggests that changes in red blood cells may contribute to this heightened danger. Researchers at Karolinska Institutet found that after several years of living with the condition, red blood cells can begin to interfere with healthy blood vessel function.
The study indicated that this harmful shift in red blood cell behavior was not present in newly diagnosed patients but emerged over time, suggesting a cumulative effect of the disease on the circulatory system. This finding helps explain why the risk of heart attacks and strokes steadily increases the longer a person has type 2 diabetes.
"Our research points to a specific molecule within red blood cells that could potentially serve as a biomarker for identifying cardiovascular risk early on," said Dr. [Fictional Name], lead author of the study and professor of cardiology at Karolinska Institutet. "This could allow for earlier interventions and more personalized treatment strategies."
Type 2 diabetes is a chronic condition that affects the way the body metabolizes glucose, a major source of energy. Over time, high blood sugar levels can lead to a host of complications, including damage to blood vessels, nerves, and organs. Cardiovascular disease is a leading cause of death among people with type 2 diabetes.
The researchers emphasized that further studies are needed to validate the potential of this molecule as a reliable biomarker. However, the current findings provide valuable insights into the mechanisms by which type 2 diabetes damages blood vessels.
"Understanding these mechanisms is crucial for developing new therapies to prevent or delay the onset of cardiovascular complications in people with diabetes," added Dr. [Fictional Name].
The Karolinska Institutet team is now focusing on larger-scale studies to confirm their findings and explore the potential of targeting red blood cell dysfunction as a therapeutic strategy. The hope is that this research will ultimately lead to improved outcomes for the millions of people worldwide living with type 2 diabetes. The study was conducted in January 2026.
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